What Are Adaptogens and Do They Actually Work?

What are adaptogens, and can they really help with stress, fatigue, or sleep? Explore five popular adaptogenic herbs, what scientific research says about their benefits, and the potential side effects and interactions to know before trying them.

Dried roots, herbs, and sliced botanicals displayed in bowls and glass jars

Key takeaways

  • Adaptogens are plants and other substances believed to help the body cope with stress, but the term doesn’t describe a scientifically proven group of treatments.[1]
  • Popular examples include ashwagandha, rhodiola, ginseng, holy basil and eleuthero.[2]
  • Some studies suggest possible benefits for stress, fatigue or sleep, but the evidence is often limited.[5]
  • A concentrated herbal extract isn’t necessarily the same as a tea or powder made from the same plant.
  • Natural supplements can cause side effects and interact with medications.[3]
In this article
  1. What Are Adaptogens?
  2. How Are Adaptogens Supposed to Work?
  3. Five Popular Adaptogenic Herbs
  4. Do Adaptogens Really Help?
  5. What Should You Know About Adaptogen Products?
  6. Safety and Possible Side Effects
  7. What This Means in Practice
  8. Frequently asked questions
  9. Final thoughts

Have you ever seen a supplement promising to help you handle stress, feel less tired or stay focused throughout the day? Maybe it contains ashwagandha, ginseng or a blend of herbs labeled adaptogens.

The idea sounds simple: take something natural and help your body deal with a busy, stressful life. But can plants really do that?

Some have been studied for stress, fatigue and sleep, with interesting results. Still, the evidence isn’t equally strong for every plant, and the word adaptogen doesn’t guarantee that a product works.

Let’s explore what adaptogens are, why people use them and what science actually tells us.

What Are Adaptogens?

Imagine you’ve had a long day. You’ve dealt with work deadlines, answered dozens of messages and still have things to finish at home.

By evening, you feel exhausted. A product promising to help your body become more resistant to stress might sound exactly like what you need.

That’s the idea behind adaptogens.

The term first appeared in Soviet research during the 1940s. Scientists wanted to find substances that might help people continue functioning under demanding conditions, such as physical effort, fatigue and stress.[1]

Today, the word is mostly associated with certain herbs and mushrooms. You’ll find it on supplement bottles, herbal drinks, powders and wellness products.

But here’s the important part: adaptogen is not a medical guarantee.

The European Medicines Agency has noted that the concept isn’t clearly established as a recognized medical treatment category. Each plant must be studied separately before we can say whether it helps with a particular problem.[1]

How Are Adaptogens Supposed to Work?

When something stressful happens, your body prepares to respond. Your heart may beat faster, you become more alert, and certain hormones help you deal with the situation.

One of these hormones is cortisol. It helps regulate energy and other important functions, and its level naturally changes throughout the day.

This response is useful. But when stress continues for a long time, you may notice that you’re sleeping poorly, finding it harder to concentrate or feeling tired more often.

Researchers are studying whether some plant compounds can influence the way the body responds to stress.[2]

For example, certain extracts have been investigated for their effects on stress-related hormones, sleep and feelings of exhaustion. However, an effect measured in a laboratory doesn’t automatically mean a supplement will help someone feel better.

Different plants may act differently, and there isn’t one proven mechanism shared by every adaptogen.[1]

Five Popular Adaptogenic Herbs

Not all adaptogens are used for the same reason. Some are promoted for relaxation, while others are advertised for energy or concentration.

Here’s a closer look at five well-known examples.

1. Ashwagandha

Ashwagandha is a plant traditionally used in Indian Ayurvedic medicine. Today, it’s one of the best-known herbs sold for stress and sleep.

Some small studies have found that certain ashwagandha extracts may help people feel less stressed or improve aspects of sleep. However, the research has limitations, and not every product has been tested.[5]

Ashwagandha can also interact with medications and may affect thyroid function. Rare cases of liver injury have been reported.[5]

For more information about its potential benefits and risks, read our guide to ashwagandha.

2. Rhodiola

Rhodiola is a plant that grows in cold, mountainous regions. It has traditionally been used in parts of Europe and Asia to help with tiredness and physical demands.

Researchers have explored whether rhodiola may help with fatigue linked to stress. Some studies have reported improvements, but the findings aren’t consistent enough to draw firm conclusions.[2]

3. Asian Ginseng

Asian ginseng has a long history in East Asian traditional medicine. It’s commonly sold in products promising more energy, better concentration and improved endurance.

Some studies have investigated its effects on fatigue and mental performance, but results are mixed. It can also cause unwanted effects, including difficulty sleeping.[6]

4. Holy Basil

Holy basil, also called tulsi, is a plant traditionally used in India. You may encounter it in herbal teas or supplements promoted for relaxation and general well-being.

A few small studies suggest possible benefits for perceived stress. However, we need larger and better-quality studies before we can be confident about these effects.[2]

5. Eleuthero

Eleuthero is sometimes called Siberian ginseng, although it’s a different plant from Asian ginseng.

It became well known through Soviet-era research on physical performance and fatigue. Today, it’s still marketed as an adaptogen, but reliable evidence for its broad stress-related benefits remains limited.[2]

Do Adaptogens Really Help?

The answer depends on the plant and what you expect it to do.

For example, an extract studied for sleep may not necessarily improve physical endurance. Similarly, a herb traditionally used for energy may not have convincing evidence that it actually reduces fatigue.

Here’s what research currently suggests.

PlantCommonly Studied ForWhat Research Suggests
AshwagandhaStress and sleepSome promising short-term results
RhodiolaStress-related fatiguePossible benefits, but inconsistent findings
Asian ginsengEnergy and concentrationMixed results
Holy basilStress and well-beingLimited evidence from small studies
EleutheroFatigue and enduranceNot enough reliable evidence

This doesn’t mean every plant on the list is ineffective. It means we still need stronger evidence to know who might benefit, how much and under what circumstances.

It’s also important to remember that a positive study doesn’t prove that every product made from the same herb works equally well.

What Should You Know About Adaptogen Products?

Imagine seeing two ashwagandha products in a shop. One is a box of herbal tea, and the other is a bottle of concentrated capsules.

They may come from the same plant, but that doesn’t mean they contain the same amounts of its natural compounds.

The way a plant is prepared can change what ends up in the final product. A tea extracts certain substances into hot water, while a concentrated extract may contain different amounts or types of compounds.

That’s why studies using one specific extract cannot automatically tell us what to expect from every tea, powder or capsule.

We explain these differences more fully in Herbal Tea vs. Herbal Supplements: What’s the Difference?

What Should You Check on a Label?

If you’re comparing herbal products, a few details are worth noticing:

  • The plant’s name: Does the label identify the exact plant?
  • The form: Is it a tea, powder or concentrated extract?
  • The amount: Does the manufacturer clearly explain how much of the ingredient is included?
  • Quality information: Is there credible testing for product identity and contaminants?
  • Other ingredients: Does the product contain several herbs or additional substances?

A supplement with more ingredients isn’t necessarily more effective. Sometimes, a longer ingredient list simply makes it harder to understand what you’re taking.

Safety and Possible Side Effects

It’s tempting to think that something made from a plant must be gentle on the body. But plants contain substances that can have real effects, including unwanted ones.

Some herbal products may interfere with medications or affect existing health conditions. Certain preparations can also cause digestive problems, sleep disturbances or other reactions.[2]

A study published in 2023 examined reported adverse reactions involving adaptogenic products taken alongside antidepressants. The researchers identified possible interactions, although the study couldn’t establish how often they occur.[3]

This is one reason it’s important not to combine herbal supplements with medications without checking their safety.

Our article on medicinal plants and modern drugs explores the wider relationship between plants, their active substances and medicines.

Extra caution is needed during pregnancy or breastfeeding and for people living with chronic health conditions.

If you regularly struggle with exhaustion, stress or poor sleep, it’s also worth exploring why these problems are happening rather than assuming a supplement will solve them.

What This Means in Practice

You don’t need to memorize the scientific names of plants or understand complicated laboratory research to make sense of adaptogens.

Start with the problem a product claims to solve.

If you’re feeling tired, ask whether the product has actually been studied for fatigue. If your main concern is sleep, look for evidence specifically related to sleep rather than general claims about stress.

For readers interested in plants traditionally used at bedtime, our guide to the best herbs for sleep examines the evidence and safety considerations in more detail.

The most useful habit is to look beyond words such as natural, balance and stress support. Ask what a product contains, what researchers have actually tested and what is still uncertain.

Frequently asked questions

Are Adaptogens the Same as Stimulants?

No. Stimulants such as caffeine can increase alertness, often relatively quickly. Adaptogens are promoted for their possible effects on the body’s response to stress, but those effects aren’t equally established for every plant.[1]

An adaptogen shouldn’t be expected to provide the immediate energy boost associated with coffee. Some herbal products may also interfere with sleep.[6]

How Long Does It Take for Adaptogens to Work?

There isn’t one answer for every adaptogen. Some studies have looked for changes after several weeks, while other plants have barely been studied in people.[2]

A company promising that an adaptogen will work within a precise number of days should be able to support that claim with reliable research on the specific product.

Can You Take Adaptogens Every Day?

Some herbs have been studied with daily use for short periods, but we often know less about their long-term safety.[5]

Whether regular use is appropriate depends on the plant, the preparation, your health and any medications you take.

Are Adaptogenic Mushrooms Proven to Work?

Mushrooms such as reishi and cordyceps are often included in products marketed for stress, energy or immune support. However, the research is still limited, and the evidence varies between different mushrooms and preparations.

Calling a mushroom adaptogenic doesn’t prove that it can prevent or treat a disease. Regulators have taken action against companies making disease claims for mushroom products.[4]

Final thoughts

Adaptogens aren’t a single type of miracle plant. They’re a group of herbs and other substances linked by the idea that they might help the body respond to stress, although that broad claim hasn’t been firmly established.

Some individual extracts have produced promising research results, but others need much more study. Understanding the difference between traditional use, marketing and scientific evidence can help you approach these products with realistic expectations.

References

  1. European Medicines Agency (2008). Reflection Paper on the Adaptogenic Concept. ema.europa.eu
  2. MSD Manual Consumer Version. Adaptogens. msdmanuals.com
  3. Siwek M, et al. (2023). Harder, Better, Faster, Stronger? Retrospective Chart Review of Adverse Events of Interactions Between Adaptogens and Antidepressant Drugs. Frontiers in Pharmacology. pmc.ncbi.nlm.nih.gov
  4. U.S. Food and Drug Administration (2020). Warning Letter to Mushroom Revival, Inc. Archived copy. web.archive.org
  5. National Center for Complementary and Integrative Health. Ashwagandha: Usefulness and Safety. nccih.nih.gov
  6. National Center for Complementary and Integrative Health. Asian Ginseng: Usefulness and Safety. nccih.nih.gov

Written by Victoria, founder and editor of RoutineHealth. This article is for general education and is not medical advice. Herbal supplements may cause side effects or interact with medications, and their safety can vary by product and individual circumstances. For persistent health concerns or questions about combining herbal supplements with medicines, consult a qualified healthcare professional. How we research and correct articles is explained in our Editorial Policy; see also our Medical Disclaimer.

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